Genetic Testing for Hereditary Colorectal Cancer
نویسندگان
چکیده
منابع مشابه
AGA technical review on hereditary colorectal cancer and genetic testing.
This literature review and the recommendations therein were prepared for the American Gastroenterological Association (AGA) Clinical Practice and Practice Economics Committee. The paper was approved by the Committee on March 20, 2001, and by the AGA Governing Board on April 18, 2001.
متن کاملGenetic counseling in hereditary nonpolyposis colorectal cancer.
Recent identification of gene mutations responsible for hereditary nonpolyposis colorectal cancer (HNPCC) has made possible the presymptomatic diagnosis of at-risk family members. If DNA testing shows that a family member is a gene carrier, that individual's lifetime cancer risk is approximately 90%. If the test is negative, the family member's cancer risk drops to that of the general populatio...
متن کاملEvaluation of a counselling protocol for predictive genetic testing for hereditary non-polyposis colorectal cancer.
OBJECTIVES To evaluate the feasibility of a reduced counselling programme for predictive genetic testing for hereditary non-polyposis colorectal cancer (HNPCC) in terms of counsellees' opinions on the extent and significance of genetic counselling and need for psychological support at different phases of the testing procedure. DESIGN Prospective follow up study with pre-test questionnaire ass...
متن کاملInterpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing.
CONTEXT Genetic testing for cancer predisposition is evolving from purely research applications to affecting clinical management. OBJECTIVE To determine how often genetic test results for hereditary nonpolyposis colorectal cancer (HNPCC) can be definitively interpreted and used to guide clinical management. DESIGN Case-series study conducted in 1996 to 1998 in which a complete sequence anal...
متن کاملValue of Genetic Testing for Hereditary Colorectal Cancer in a Probability-Based US Online Sample.
BACKGROUND . While choices about genetic testing are increasingly common for patients and families, and public opinion surveys suggest public interest in genomics, it is not known how adults from the general population value genetic testing for heritable conditions. We sought to understand in a US sample the relative value of the characteristics of genetic tests to identify risk of hereditary c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Surgical Oncology Clinics of North America
سال: 2009
ISSN: 1055-3207
DOI: 10.1016/j.soc.2009.08.001